Studies in which animals are allowed to die without pain relief. B The "Animal Welfare Act" of 1966 is enforced by the USDA and was enacted to regulate the sale of pets to research facilities, and as such, do not regulate mice, rats (or birds), bred for use in research. All answers are correct. Which of the following statements about the postoperative period is FALSE? Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? C If an IACUC votes to suspend a protocol or animal activity, its decision cannot be overturned by any administrator at the organization (including the Institutional Official). IACUCs may allow quick decapitation with scissors for euthanasia of altricial rodent neonates (up to ten days of age). The IACUC Rodents are susceptible to subclinical infections after surgery. If an investigator sees an animal that appears to be in immediate danger, what action should be taken first? Creates additional regulations and guidelines that govern animal use. C. A change in personnel. Which of the following statements about caging for mice reflect the information that is in the Guide for the Care and Use of Laboratory Animals? What does "IACUC" stand for? Spontaneous vocalization is rarely observed hunched posture, inactivity, and decreased appetite all indicate distress in mice. Which of the following is an injectable anesthetic agent? C. National Science Foundation (NSF) A. Which statement is true regarding anesthesia in mice? Blood collections should be spaced far enough apart to prevent which of the following? A. Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries? Which statement concerning survival experimental surgery is FALSE? What is the easiest way to induce gas anesthesia for a mouse? A. C The criteria used for intervention in research studies to prevent unnecessary pain and distress are called "humane endpoint criteria" because they describe when it is time to: euthanize an animal to prevent suffering; discontinue a painful procedure; and/or remove an animal from a study. It provides a mechanism for peer evaluation of animal care and use programs B. Which of the following best summarizes the information that must be provided when a database search is used to document a lack of alternatives? D. Observation studies of normal primate behavior. B. This animal rights-related article is a stub. Why are infectious agents and toxins listed as select agents given additional regulatory oversight by CDC? D. If an IACUC votes to suspend a protocol or animal activity, that decision can be overturned by any administrator at the organization. Which of the following would provide longer-acting pain relief in mice? [1] The Guide is written by the National Research Council of the U.S. National Academy of Sciences. C. Institutional Animal Care and Utilization Corps A. D. Dogs must be provided additional exercise regardless of the floor area of the cage. The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Wild birds. Which of the following is a mandated IACUC activity? Modify the animal protocol form and keep a copy for their files. C. The list of citations and the date of the search. D. Notify the Institutional Official. which of the following is true of aaalac international? Before any use of the animals for the project begins. BB creams are all-in-one beauty products that can With so many things to do in Miami, youll be able to create the perfect vacation package. D A proper search for alternatives to procedures that cause more than momentary pain or distress includes using database(s) appropriate for the field of study (e.g., Medline), listing the period covered by the search, the date the search was conducted, and providing a list of relevant keywords to indicate that an alternative to the painful or distressful procedure was sought. Unnecessary duplication of animal experiments is not allowed. A. Daily observations are usually recorded during the postoperative period. A change in the principal investigator Restraint can be used as a normal component of animal housing, Restraint for brief periods of time during experimental procedures do not need to be mentioned in the animal use protocol. Conduct reviews of the animal care and use program on a semiannual basis, Institutional Animal Care and Use Committee. Which of the following is considered a minor change that would not require formal IACUC review and approval? C. Dry ice is an acceptable source of CO2 for euthanasia. In fact, if an IACUC votes to suspend a protocol or animal activity, that decision cannot be overturned by any administrator at the organization. Which statement is true regarding the conduct of surgery in mice? Which of the following sets of IACUC members are required by the AWA and/or PHS? Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? C. Commercial antibody enterprises are not required to follow PHS or USDA guidelines. A. UsingAAVrh10,Raetal.achievedgreaterefcacyin mice by either increasing the dose via combined route of administration,27 combination of systemic AAVrh10 with . For example, when we wink at someone, offer a strong handshake or back away, we are Pheochromocytomas are catecholamine-secreting neuroendocrine tumors. B. B. D. Each organization must offer an Occupational Health and Safety Program for personnel who have significant contact with laboratory animals. Accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International has long been trumpeted as being the "gold standard" C. Over enthusiastic grooming of dorsal fur or haircoat. Which measure can correct respiratory depression in anesthetized mice? Locked bedroom doors are a common sight in many homes. A. A. Determine when emergency IACUC meetings must be scheduled. 3 percent Driving in the summer, winter, or rainy season may be to blame for the unpleasant odor inside the car. The overlap between groups has ______ in americas residential neighborhoods and workplaces. Is that even a thing? Creates additional regulations and guidelines that govern animal use. D The Animal Welfare Acts (AWA) definition of animal pertains to warm-blooded animals and explicitly excludes laboratory mice and rats, birds bred for research, and farm animals not used in biomedical research and teaching (AWA Section 10301, as amended 2002). The Council conducts on-site visits and extensive evaluations, and provides ongoing advice to help organizations achieve and maintain accreditation. Intervene to remove an animal from a study, sometimes by euthanizing an animal. hose organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. Give the BNAT exam to get a 100% scholarship for BYJUS coursesNo worries! What diameter spherical balloon will just support the total weight? The name change reflected the organizations recognition and expansion in other countries, and its commitment to enhancing life sciences and quality animal care around the world. IACUCs are not mandated to write the basic science portions of grant applications or animal use protocols for investigators. The IACUC is charged with ensuring that all personnel involved in animal research are offered enrollment in the organizations occupational health program. In this edition, we will bring you up to speed on AO VET activities over the past five months. Which of the following is a role of Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International? Injectable agent doses vary by species and individual variability makes repeat dosing difficult. A simple rule to prevent excess blood collection in an animal is to collect no more than what percentage of body weight as blood at one time? Major survival surgery on rodents, non-survival surgery, and major non-survival surgery on non-rodent mammals do not require such a dedicated suite. Complete the following nuclear equations. Which of the following statements regarding the use of restraint on animals in a research study is FALSE? Protection for those who report misuse of animals or noncompliance is mandated by the Animal Welfare Regulations, Brunner and Suddarth's Textbook of Medical-Surgical Nursing. The attending veterinarian C. Sanitizing the area after use can be left to the night housekeeping crew, as long as they do the job within 12 hours. Contracting with a commercial enterprise to produce custom antibodies requires IACUC approval. A microchip is injected subcutaneously with a hypodermic needle. The 2015 memorandum of understanding between the NIH and NSF also mandates that organizations receiving NSF funding for animal research projects comply with the PHS Policy. A change from non-survival to survival surgery B. Humane methods of animal experimentation A. What statement regarding adjunctive methods of euthanasia is TRUE? Which statement is true regarding care procedures for mice undergoing surgery? The name change reflected the organization's recognition in other countries, and its commitment to enhancing life sciences and quality animal care around the world. Which of the following statements concerning euthanasia in neonates is true? Which of the following is a role of AAALAC International? Which of the following is a mandated IACUC activity? Institutional Animal Control and Use Committee C Category D of the USDA report form applies to " animals upon which experiments, teaching, research, surgery, or tests were conducted involving accompanying pain or distress to the animals and for which appropriate anesthetic, analgesic, or tranquilizing drugs were used. Mice are physiologically unable to vomit, they have no risk for respiratory aspiration of vomitus under anesthesia. Which of the following is not a good justification for housing animals individually? Participating institutions receive an independent, unbiased expert assessment, and those that meet or exceed applicable standards are awarded accreditation. AAALAC Accreditation demonstrates to funding agencies and the general public that the animal care provided goes beyond minimum regulatory requirements. Scientific reasons On this Wikipedia the language links are at the top of the page across from the article title. The Council is pleased to inform you that the program conforms with AAALAC International standards as set forth by the Guidefor the Care and Use of Laboratory Animals, NRC 2011. Therefore, FULL ACCREDITATION shall continue. Which of the following best describes the purpose of the federally mandated "alternatives search" in an animal protocol? However, the latter should be performed under anesthesia and is not a preferred site because of the potential for damage to the eye when the technique is not done properly or when used repeatedly. AAALAC International was founded in 1966 and is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. A public relations specialist is not part of this mandate. No treatment is available should a human become exposed. D. The use of computer modeling software to substitute for animal experiments. Compared to adults, neonates are much more susceptible to low oxygen levels, and quickly succumb to death by carbon dioxide inhalation. This list does not contain all possible questions you yourself may encounter. The Council also appoints a roster of ad hoc consultants. AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. A. B Per PHS Policy and USDA Animal Welfare Regulations, the IACUC is given responsibility for ensuring that research personnel are properly trained to perform animal procedures. Julie S Snyder, Linda Lilley, Shelly Collins, Explain the important distinctions between **periods and groups of the periodic table**. D. To search for procedures that may replace the use of animals, reduce the number of animals used, or refine the methodology to minimize animal pain or distress. Sedation causes vasodilation which helps make the tail vein easier to find. Which of the following is NOT an example of reduction per the three Rs of Russell and Burch? Some types of changes to an animal protocol can be approved administratively by veterinary verification and consultation. C. AAALAC. The Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Institute for In Vitro Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily interested in what area? A mouse with a moderately painful condition may appear and behave normally. A dedicated surgery suite must be used for which surgery? Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? Which organization is responsible for monitoring institutional compliance with PHS Policy? This is done through AAALAC's voluntary accreditation process in which research programs demonstrate that they meet the minimum standards required by law, and are also going the extra step to achieve excellence in animal care and use. B. Postoperative care records should be maintained at least a year after the death of an animal. Which of the following is a role of AAALAC International? This section explains the subject of divorce law in New Jersey. Which of the following methods is considered acceptable for euthanizing mice? B. A. A. B. Nonaseptic technique for survival surgery in mice is permitted by the Guide for the Care and Use of Laboratory Animals. Which of the following institutions must follow PHS guidelines for animal research? The Council also appoints a roster of ad hoc Consultants/Specialists. Which of the following is NOT a reason to provide environmental enrichment? ", Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? Either general or regional (local) anesthesia is required to prevent pain. Surgical procedures should be planned and approved by the IACUC before they are performed. C. A public relations specialist, veterinarian, practicing scientist with experience in animal research, and person who is not a scientist. A. D Organizations receiving funds from PHS agencies are required to comply with the PHS Policy. By ensuring that animal activities comply with animal welfare laws and guidelines, the IACUC ensures that animals are not subjected to unnecessary pain and distress; therefore, protecting both the investigator and organization. Which of the following sets of IACUC members are required by the AWA and/or PHS? A. The Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. B. What is NOT a recommendation for postoperative care of mice? The library service used to perform the search, the date of the search, and the key words used. One book, The Guide for the Care and Use of Laboratory Animals serves as the basic standard represented by AAALAC accreditation. typically transmitted from animals to humans? The Guide for the Care and Use of Laboratory Animals provides: The basic information needed to develop an institutional occupational health and safety program. A. Cages with water bottle watering systems The balloon material has a mass of $60 \mathrm{~g} / \mathrm{m}^2$. B. Which of the following statements is/are TRUE regarding preparation of a mouse for surgery? Which of the following represents an appropriate technique for subcutaneous injections in mice? What is a primary mission of the Animal Welfare Information Center (AWIC), a part of USDA? B. Inoculation of nonrecombinant infectious agents into animals Which types of animals must have access to environmental enrichment, as mandated by the Animal Welfare Regulations? A. B. A. Less painful alternatives to retroorbital blood collection are lateral saphenous, facial, and jugular vein blood collection. To share information with other regulatory agencies The AAALAC International Fellowship recognizes two outstanding Registry participants each year, one IAT Registered (RAnTech) technologist and one AALAS Registered (RALAT, RLAT, RLATG, or CMAR) technician or manager, who have made (or have the potential to make) significant contributions to the field of laboratory animal care and use. A veterinarian, practicing scientist with experience in animal research, person who is not a scientist, and person who is not affiliated with the organization. Methods for substance administration in rats and mice are outlined in which document? A. Behavioral reasons (such as aggression by C57BL/6 male mice) If an organization accepts PHS funds or is registered with the USDA as a research organization, any protocol suspension must be reported by the Institutional Official to OLAW and USDA. D. History and tactics of animal activist groups (such as PeTA and HSUS). Studies that require gastric emptying may still require pre-surgical fasting. Which of the following statements is true if an investigator wants to use a human clinical area for animal research? Adjunctive methods of euthanasia, such as pithing frogs, should only be performed on animals that are already unconscious. B. C. Mice will continue to groom themselves, even when in pain or distress. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. For some, animal research is a controversial topic. The program must include time spent outside. To conduct voluntary evaluations of institutional animal care and use programs. The Council is divided into North American, Pacific Rim and European Sections. B. A. Remove the animal from the threat if safe to do so and contact the attending veterinarian or IACUC. The various behavioral forms that nonverbal communication takes are referred to as nonverbal, Why give alpha blocker before beta blocker in pheochromocytoma. The Public Health Service (OLAW) A. The IACUC can exempt an animal for scientific reasons. C. Conduct reviews of the animal care and use program on a semiannual basis Thermal support is an important aspect of postoperative support. Female mice have how many pairs of nipples? Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be They are methods that are acceptable as a follow-up procedure for ensuring death. D. It is unacceptable to decapitate neonates with scissors, even with IACUC approval. Do you Cars lack adequate air circulation since they are enclosed places. A. Collecting tail snips from adult rodents for genotyping under local or general anesthesia. C. Before any procedures are performed Which of the following sets of IACUC members are required by the AWA and/or PHS? Surgery that penetrates and exposes a body cavity or produces substantial physical impairment is defined as what kind of surgery? which of the following is true of aaalac international? AAALAC International relies on three primary standards used by the Council to evaluate programs: UTSA & AAALAC Accreditation | Date of Inital Accrediation: October 26, 2010. A. A straight needle is preferred for oral gavage in a 18 gram mouse because it prevents trauma to the esophagus. Research utilizing animals is a privilege, not a right, and the IACUC has the responsibility to ensure that research, testing, and educational activities involving the use of animals are performed according to the highest standards. A. Endpoint criteria describe when it is time to do what? This concept represents the beginning of the effort to form an accreditation program for laboratory animal care and use. They do not apply to nonrecombinant ones. D. Food should be withheld prior to surgery, but not water. Quickly and professionally. Leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care (AAALAC) in 1965, as a private, nonprofit organization. Performing or sponsoring research into alternatives to animal use for research and testing. A. C. Work in pairs. Which of the following statements is TRUE? C A mandated IACUC function is to conduct reviews of the animal care and use program on a semiannual basis. A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. Members of the Council are chosen to serve based on their extensive experience in the fields of veterinary medicine, laboratory animal science or animal research, and their commitment to humane animal care and use. B. To conduct voluntary evaluations of institutional animal care and use programs. AAALAC International standards for accreditation are set forth by the Guide for the Care and Use of Laboratory Animals, established by the U.S. National Research Council in 2011. When assessing a client with partial-thickness burns over 60% of the body, which finding should the nurse report immediately? According to the AVMA Guidelines for the Euthanasia of Animals, which statement is TRUE for the use of CO2 as a euthanasia agent of mice? A. A. Which of the following is a role of AAALAC International? D. A change in surgical anesthetic. C. Non-survival surgery The Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Which of the following sets of IACUC members are required by the AWA and/or PHS? Which statement is true about mice in the age range of 6-10 days? C. Before any use of the animals for the project begins. Which of the following is true of AAALAC International? What is the maximum number of emission lines possible for a hydrogen atom in the n 4 state? Which of the following statements is TRUE about injectable anesthetics compared with gaseous anesthetics used with mice? Which statement about the Occupational Health and Safety Program is false? Mouse urine and pelt proteins are an allergic hazard to people. Permission should be obtained from the IACUC and clinical administrators responsible for the area. Which statement is true regarding venipuncture procedures in mice: What is the recommended depth for inserting a needle for IP injection of mice? You can get your paper edited to read like this. Accredited Which of the following statements is TRUE about blood collection in mice? B. B. Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (Guide, NRC 2011); the Guide for the Care and Use of Agricultural Animals in Research and Teaching (Ag Guide, FASS 2010); and the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes, Council of Europe (ETS 123). B. IACUCs are not responsible for investigating allegations of mistreatment, misuse, or noncompliance, as it is the investigators role to do so. C. USDA regulations require that all mice be fasted prior to surgery. Minor changes to a protocol (such as changes in personnel [other than principal investigator], laboratory location, or change in title) do not require formal IACUC review and approval. It requires annual reports from its accredited facilities C. It conducts site visits every 3 years D. It is a government - sponsored agency 16. Over distension of the urinary and gall bladders. What is generally a superior anesthesia choice for mice undergoing major surgical procedures? Which is a TRUE statement below regarding assessment of pain or distress in mice: The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care (AAALAC), as a private, nonprofit organization. What document provides the guidelines for working with infectious diseases in animal research?

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