Am J Clin Nutr 1983;38:257-63. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. 2019;13(1):175-182. Pediatr Infect Dis J 1997;16:1103-7. Chandra RK. Hickson M, D'Souza AL, Muthu N, et al. Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 improve abdominal pain severity and symptomology in irritable bowel syndrome: Randomized controlled trial. Clin Exp Allergy 2012;42(1):112-22. Lactobacillus preparations may assist in reestablishing the normal physiologic and bacterial flora of the intestinal tract. Inflammation of an artificial rectum surgically created in people with inflammatory bowel disease (pouchitis): A combination probiotic containing, Lactobacillus, Bifidobacterium, and Streptococcus species (VSL#3), has been taken twice daily for up to one year. View abstract. Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women. Alak JI, Wolf BW, Mdurvwa EG, et al. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Szajewska H, Kotowska M, Mrukowicz JZ, et al. Inverse association of H2O2-producing Lactobacilli and vaginal Escherichia coli colonization in women with recurrent urinary tract infections. View abstract. View abstract. Niedzielin K, Kordecki H, Birkenfeld B. Risa-Bid, RisaQuad, Superdophilus, Acidophilus with Pectin, Novaflor, Acidophilus Extra Strength, Flora-Q 2, RisaQuad 2, Acidophilus Probiotic Blend, Florajen Acidophilus. Lactobacillus kefiri LKF01 (Kefibios) for prevention of diarrhoea in cancer patients treated with chemotherapy: A prospective study. Inverse association of H2O2-producing Lactobacilli and vaginal Escherichia coli colonization in women with recurrent urinary tract infections. Barrett JS, Canale KE, Gearry RB, et al. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. 2013 26;13:56. Am J Gastroenterol 2008;103(1):178-89. Romano C, Ferrau' V, Cavataio F, et al. Persistence of colonization of human colonic mucosa by a probiotic strain, Lactobacillus rhamnosus GG, after oral consumption. J Am Coll Nutr 1996;15:408-12. Pregnant and lactating women should be advised that usage of this drug should only be in situations where the benefits clearly outweigh the risks. Scand J Immunol 1996;43:687-9. Can J Gastroenterol 2007;21(11):732-736. View abstract. Szajewska H, Gyrczuk E, Horvath A. Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind,placebo-controlled trial. For high cholesterol: A mixture of three strains of Lactobacillus plantarum containing a total daily dose of 1.2 billion live cells has been used for 12 weeks. Deguchi R, Nakaminami H, Rimbara E, Noguchi N, Sasatsu M, Suzuki T, Matsushima M, Koike J, Igarashi M, Ozawa H, Fukuda R, Takagi A. Pediatrics 2005;115:178-81. View abstract. 2021;10(1):36-47. View abstract. View abstract. A successful probiotic would fulfill the following criteria: Human or food origin Stability in gastric acid 2015;33:25. Jung GW, Tse JE, Guiha I, Rao J. J Health Popul Nutr. Lactobacillus is a bacteria that exists naturally in the body, primarily in the intestines and the vagina. lactobacillus acidophilus and bulgaricus Lactobacillus acidophilus and bulgaricus has been used as a probiotic to aid in digestion, which can prevent the growth of harmful bacteria, Be Mohamad Nor MH, Ayob N, Mokhtar NM, et al. View abstract. View abstract. BMC Womens Health 2008;8:3. McFarland LV. Velraeds MM, van der Mei HC, Reid G, Busscher HJ. View abstract. Aliment Pharmacol Ther 2003;17:895-904. . Technological and biological evaluation of tablets containing different strains of lactobacilli for vaginal administration. Osterlund P, Ruotsalainen T, Korpela R, et al. Beausoleil, M., Fortier, N., Guenette, S., L'ecuyer, A., Savoie, M., Franco, M., Lachaine, J., and Weiss, K. Effect of a fermented milk combining Lactobacillus acidophilus Cl1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: a randomized, double-blind, placebo-controlled trial. View abstract. Safety and tolerance of Lactobacillus reuteri supplementation to a population infected with the human immunodeficiency virus. View abstract. View abstract. Clin Infect Dis 1999;28:1159-60. J Spinal Cord Med 2000;23:136-41. Biomed Pharmacother 2021;141:111915. Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Also has been used for treatment of infectious diarrhea, ulcerative colitis, irritable colon, diverticulitis, colostomies with either diarrhea or constipation, functional constipation, mucous or spastic diarrhea, and diarrhea following amebiasis. Kalima P, Masterton RG, Roddie PH, et al. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated diarrhoea. J Dairy Sci 1997;80:1537-45. View abstract. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. Low-dose balsalazide plus a high-potency probiotic preparation is more effective than balsalazide alone or mesalazine in the treatment of acute mild-to-moderate ulcerative colitis. Meydani SN, Ha WK. Pirotta M, Gunn J, Chondros P, et al. PLoS One 2012;7(4):e34540. L. acidophilus vaginal, A digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori). View abstract. Arvola T, Laiho K, Torkkeli S, et al. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. 2013;32(6):928-34. Am J Gastroenterol 2002;97:2744-9. View abstract. Gupta K, Stapleton AE, Hooton TM, et al. Effect of Lactobacillus sakei supplementation in children with atopic eczema-dermatitis syndrome. Ask a doctor before using this product if you are pregnant or breast-feeding. Immunologic effects of yogurt. 1980) with the type strain of Lactobacillus amylovorus (Nakamura 1981). Antibiotics are used to reduce harmful bacteria in the body. Caries Res. 2014;40(2):200-7. Reid G, Bruce AW, Taylor M. Influence of three-day antimicrobial therapy and lactobacillus vaginal suppositories on recurrence of urinary tract infections. 2013;17(2):114-22. Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis. Health Technol Assess 2013;17(57):1-140. Sex Transm Dis 1992;19:146-8.. View abstract. Lactobacillus acidophilus has been used in alternative medicine as a possibly effective aid (in children or adults) in preventing Rev Esp Enferm Dig. Saxelin M, Chuang NH, Chassy B, et al. Acidophilus is considered a good bacteria. de Roos NM, Katan MB. Eur J Clin Nutr. Current and potential uses of probiotics. Nutritional and therapeutic aspects of lactobacilli. Nutr Res 2002;22:393-403. Madsen KL, Doyle JS, Jewell LD, et al. Kalliomaki M, Salminen S, Poussa T, et al. Helicobacter. View abstract. Linn YH, Thu KK, Win NHH. Administer orally, preferably with milk, fruit juice, or water. Hatakka K, Savilahti E, Ponka A, et al. McFarland LV. Kasravi FB, Adawi D, Molin G, et al. Acta Paediatr. de Roos NM, Katan MB. Yli-Knuuttila H, Snall J, Kari K, Meurman JH. Nutr Cancer 1996;25:197-204. Schultz M, Sartor RB. Obtain periodic urine cultures, BUN, creatinine clearance, CBC, Hgb, and Hct. Drug class: Antidiarrhea Agents Super Tips to Boost Digestive Health: Bloating, Constipation, and More. View abstract. information and will only use or disclose that information as set forth in our notice of Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. Efficacy of oral metronidazole with vaginal clindamycin or vaginal probiotic for bacterial vaginosis: randomised placebo-controlled double-blind trial. View abstract. J Assoc Physicians India 2013;61(10):708-12. Reid G, Bruce AW, Taylor M. Influence of three-day antimicrobial therapy and lactobacillus vaginal suppositories on recurrence of urinary tract infections. View abstract. View abstract. Infect Immun 1989;57:2447-51. View abstract. 2014;103(3):249-55. Oral Microbiol Immunol 2002;17:9-15. Lactobacillus acidophilus should not be used in place of medication prescribed for you by your doctor. 2013;18(4):280-4. View abstract. Land MH, Rouster-Stevens K, Woods CR, et al. View abstract. Acta Paediatr 2010;99:1135-8. View abstract. Michael DR, Jack AA, Masetti G, et al. This includes people with HIV/AIDS or people who have taken medicines to prevent rejection of a transplanted organ. Clin Infect Dis 1996;22:564-6. J Urol 1987;138:330-5. View abstract. Am J Clin Nutr 2000;71:861-72. Lactobacillus rhamnosus infection in a child following bone marrow transplant. View abstract. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Dose-response efficacy of a proprietary probiotic formula of Lactobacillus acidophilus CL 1285 and Lactobacillus casei LBC80R for antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea prophylaxis in adult patients. Ann Med 1990;22:53-6.. View abstract. J Pediatr Gastroenterol Nutr 1995;21:224-6. 2018;9(5):697-706. Eur J Clin Nutr. View abstract. Another cool skill of Lactobacillus acidophilus is it produces the enzyme lactase. pii: E887. Double-blind,randomised clinical assay to evaluate the efficacy of probiotics in preterm newborns weighing less than 1500 g in the prevention of necrotising enterocolitis. Probiotic bacteria down-regulate the milk-induced inflammatory response in milk-hypersensitive subjects but have an immunostimulatory effect in healthy subjects. For eczema (atopic dermatitis): A specific strain of Lactobacillus rhamnosus, Lactobacillus GG (Culturelle), has been used. View abstract. When considering the use of herbal supplements, seek the advice of your doctor. We comply with the HONcode standard for trustworthy health information. View abstract. View abstract. View abstract. 1. 2013 26;13:56. Kim HJ, Camilleri M, McKinzie S, et al. View abstract. Appl Environ Microbiol 1999;65:351-4. Hudault S, Lievin V, Bernet-Camard MF, Servin AL. View abstract. View abstract. Preparations containing Lactobacillus acidophilus with or without L. bulgaricus are used for treatment of uncomplicated diarrhea, particularly that caused by modification of the intestinal flora by antibiotics. Parent D, Bossens M, Bayot D, et al. View abstract. However, research has shown that lactobacillus acidophilus may not be effective in treating these conditions. Jaisamrarn U, Triratanachat S, Chaikittisilpa S, Grob P, Prasauskas V, Taechakraichana N. Ultra-low-dose estriol and lactobacilli in the local treatment of postmenopausal vaginal atrophy. Wang YH, Huang Y. Probiotics for the Primary and Secondary Prevention of C. difficile Infections: A Meta-analysis and Systematic Review. View abstract. Med Mal Infect 2013;43(4):171-3. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Other uses not proven with research have included treating indigestion, urinary tract infections, intestinal problems in premature babies, high cholesterol, lyme disease, cold sores, acne, cancer, the common cold, and other conditions. Shornikova AV, Casas IA, Isolauri E, et al. View abstract. View abstract. Losada MA, Olleros T. Towards a healthier diet for the colon: the influence of fructooligosaccharides and lactobacilli on intestinal health. 2017;64(3):413-417. Kasravi FB, Adawi D, Molin G, et al. BMC Gastroenterol. J Am Coll Nutr 2001;20:149-56. Brand names: Acidophilus, Bacid (LAC), Florajen, Flora-Q, Lactinex, Pediatrics 2013;132(3):e666-76. View abstract. Lower doses might not be as effective. How to Lower Your Chances of Getting Crohns Flares, Ulcerative Colitis: Problem Foods to Avoid, 3 Things That May Trigger Ulcerative Colitis, How Biologics Tame Inflammation in the Gut. Effect of Lactobacillus on the incidence and severity of acute rotavirus diarrhoea in infants. Allen SJ, Wareham K, Wang D, Bradley C, Hutchings H, Harris W, Dhar A, Brown H, Foden A, Gravenor MB, Mack D. Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised, double-blind, placebo-controlled, multicentre trial. Effect of synbiotic in constipated adult women - a randomized, double-blind, placebo-controlled study of clinical response. 2014;30(4):189-94. Effect of probiotic Lactobacillus strains in children with atopic dermatitis. Am J Clin Nutr 2001;73;1124S-1130S. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. JAMA. 2013;18(4):280-4. Sullivan A, Barkholt L, Nord CE. Also, a specific beverage containing Lactobacillus plantarum (ProViva, Skanemejerier, Sweden) has been taken in doses of 125-200 mL once or twice daily, or capsules containing 10 billion CFU Lactobacillus plantarum once daily, for 4 weeks. Nutr J. nov. and Lactobacillus johnsonii sp. Acidophilus is a bacteria naturally found in your body. Elazab N, Mendy A, Gasana J, Vieira ER, Quizon A, Forno E. Probiotic administration in early life, atopy, and asthma: a meta-analysis of clinical trials. Am J Gastroenterol 2006;101:812-22. Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pylori infection. Effect of Lactobacillus plantarum 299v on colonic fermentation and symptoms of irritable bowel syndrome. Majamaa H, Isolauri E. Probiotics: a novel approach in the management of food allergy. Videlock EJ, Cremonini F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Medications that decrease the immune system can increase your chances of getting sick from bacteria and yeast. Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis. Rosenfeldt V, Michaelsen KF, Jakobsen M, et al. Tursi A, Brandimarte G, Giorgetti GM, et al. WebMD does not provide medical advice, diagnosis or treatment. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea-predominant irritable bowel syndrome. Efficacy of a standardized extract of Matricariae chamomilla L., Melissa officinalis L. and tyndallized Lactobacillus acidophilus (HA122) in infantile colic: an open randomized controlled trial. Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice. 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